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Structural basis of Type IV CRISPR RNA biogenesis by a Cas6 endoribonuclease

Prokaryotic CRISPR-Cas adaptive immune systems rely on small non-coding RNAs derived from CRISPR loci to recognize and destroy complementary nucleic acids. However, the mechanism of Type IV CRISPR RNA (crRNA) biogenesis is poorly understood. To dissect the mechanism of Type IV CRISPR RNA biogenesis,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:RNA Biol
Hauptverfasser: Taylor, Hannah N., Warner, Emily E., Armbrust, Matthew J., Crowley, Valerie M., Olsen, Keith J., Jackson, Ryan N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779396/
https://ncbi.nlm.nih.gov/pubmed/31232162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2019.1634965
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