Structural basis of Type IV CRISPR RNA biogenesis by a Cas6 endoribonuclease

Prokaryotic CRISPR-Cas adaptive immune systems rely on small non-coding RNAs derived from CRISPR loci to recognize and destroy complementary nucleic acids. However, the mechanism of Type IV CRISPR RNA (crRNA) biogenesis is poorly understood. To dissect the mechanism of Type IV CRISPR RNA biogenesis,...

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Udgivet i:RNA Biol
Main Authors: Taylor, Hannah N., Warner, Emily E., Armbrust, Matthew J., Crowley, Valerie M., Olsen, Keith J., Jackson, Ryan N.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779396/
https://ncbi.nlm.nih.gov/pubmed/31232162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2019.1634965
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