Structural basis of Type IV CRISPR RNA biogenesis by a Cas6 endoribonuclease

Prokaryotic CRISPR-Cas adaptive immune systems rely on small non-coding RNAs derived from CRISPR loci to recognize and destroy complementary nucleic acids. However, the mechanism of Type IV CRISPR RNA (crRNA) biogenesis is poorly understood. To dissect the mechanism of Type IV CRISPR RNA biogenesis,...

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Bibliografiska uppgifter
I publikationen:RNA Biol
Huvudupphovsmän: Taylor, Hannah N., Warner, Emily E., Armbrust, Matthew J., Crowley, Valerie M., Olsen, Keith J., Jackson, Ryan N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2019
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779396/
https://ncbi.nlm.nih.gov/pubmed/31232162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2019.1634965
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