Structural basis of Type IV CRISPR RNA biogenesis by a Cas6 endoribonuclease

Prokaryotic CRISPR-Cas adaptive immune systems rely on small non-coding RNAs derived from CRISPR loci to recognize and destroy complementary nucleic acids. However, the mechanism of Type IV CRISPR RNA (crRNA) biogenesis is poorly understood. To dissect the mechanism of Type IV CRISPR RNA biogenesis,...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Taylor, Hannah N., Warner, Emily E., Armbrust, Matthew J., Crowley, Valerie M., Olsen, Keith J., Jackson, Ryan N.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779396/
https://ncbi.nlm.nih.gov/pubmed/31232162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2019.1634965
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