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Fitting CRISPR-associated Cas3 into the Helicase Family Tree
Helicases utilize NTPs to modulate their binding to nucleic acids and many of these enzymes also unwind DNA or RNA duplexes in an NTP-dependent fashion. These proteins are phylogenetically related but functionally diverse, with essential roles in virtually all aspects of nucleic acid metabolism. A n...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3984625/ https://ncbi.nlm.nih.gov/pubmed/24480304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2014.01.001 |
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