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Fitting CRISPR-associated Cas3 into the Helicase Family Tree

Helicases utilize NTPs to modulate their binding to nucleic acids and many of these enzymes also unwind DNA or RNA duplexes in an NTP-dependent fashion. These proteins are phylogenetically related but functionally diverse, with essential roles in virtually all aspects of nucleic acid metabolism. A n...

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Detalhes bibliográficos
Main Authors: Jackson, Ryan N., Lavin, Matthew, Carter, Joshua, Wiedenheft, Blake
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984625/
https://ncbi.nlm.nih.gov/pubmed/24480304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2014.01.001
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