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Conformational Dynamics of DNA Binding and Cas3 Recruitment by the CRISPR RNA-guide Cascade Complex
Bacteria and archaea rely on CRISPR (clustered regularly interspaced short palindromic repeats) RNA-guided adaptive immune systems for sequence specific elimination of foreign nucleic acids. In Escherichia coli, short CRISPR-derived RNAs (crRNAs) assemble with Cas (CRISPR-associated) proteins into a...
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| Publicado no: | ACS Chem Biol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5815893/ https://ncbi.nlm.nih.gov/pubmed/29035497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00649 |
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