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A Hyperactive Form of unc-13 Enhances Ca(2+) Sensitivity and Synaptic Vesicle Release Probability in C. elegans
Munc13 proteins play several roles in regulating shortterm synaptic plasticity. However, the underlying molecular mechanisms remain largely unclear. Here we report that C. elegans UNC-13L, a Munc13-1 ortholog, has three domains that inhibit synaptic vesicle (SV) exocytosis. These include the X (sequ...
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| 出版年: | Cell Rep |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6779330/ https://ncbi.nlm.nih.gov/pubmed/31509756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.08.018 |
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