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Position of UNC-13 in the active zone regulates synaptic vesicle release probability and release kinetics

The presynaptic active zone proteins UNC-13/Munc13s are essential for synaptic vesicle (SV) exocytosis by directly interacting with SV fusion apparatus. An open question is how their association with active zones, hence their position to Ca(2+) entry sites, regulates SV release. The N-termini of maj...

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Detalhes bibliográficos
Main Authors: Zhou, Keming, Stawicki, Tamara M, Goncharov, Alexandr, Jin, Yishi
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3821175/
https://ncbi.nlm.nih.gov/pubmed/24220508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01180
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