Wird geladen...
A network of phosphatidylinositol 4,5-bisphosphate binding sites regulates gating of the Ca(2+)-activated Cl(−) channel ANO1 (TMEM16A)
ANO1 (TMEM16A) is a Ca(2+)-activated Cl(−) channel that regulates diverse cellular functions including fluid secretion, neuronal excitability, and smooth muscle contraction. ANO1 is activated by elevation of cytosolic Ca(2+) and modulated by phosphatidylinositol 4,5-bisphosphate [PI(4,5)P(2)]. Here,...
Gespeichert in:
| Veröffentlicht in: | Proc Natl Acad Sci U S A |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2019
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6778221/ https://ncbi.nlm.nih.gov/pubmed/31515451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904012116 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|