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Lipids and ions traverse the membrane by the same physical pathway in the nhTMEM16 scramblase

From bacteria to mammals, different phospholipid species are segregated between the inner and outer leaflets of the plasma membrane by ATP-dependent lipid transporters. Disruption of this asymmetry by ATP-independent phospholipid scrambling is important in cellular signaling, but its mechanism remai...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Jiang, Tao, Yu, Kuai, Hartzell, H Criss, Tajkhorshid, Emad
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628016/
https://ncbi.nlm.nih.gov/pubmed/28917060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28671
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