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The nhTMEM16 Scramblase Is Also a Nonselective Ion Channel
The TMEM16 family comprises Ca(2+)-activated Cl(−) channels and phospholipid scramblases. The crystal structure of a fungal homolog, nhTMEM16, revealed an important architectural feature of this protein family in the form of a bilayer-spanning hydrophilic groove that is directly exposed to the membr...
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| Veröffentlicht in: | Biophys J |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5103024/ https://ncbi.nlm.nih.gov/pubmed/27806273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.09.032 |
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