Phosphatidylinositol 4,5-bisphosphate, Cholesterol, and Fatty Acids Modulate The Calcium-Activated Chloride Channel TMEM16A (ANO1)

The TMEM16A-mediated Ca(2+)-activated Cl(−) current drives several important physiological functions. Membrane lipids regulate ion channels and transporters but their influence on members of the TMEM16 family is poorly understood. Here we have studied the regulation of TMEM16A by phosphatidylinosito...

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Bibliographic Details
Published in:Biochim Biophys Acta
Main Authors: De Jesús-Pérez, José J., Cruz-Rangel, Silvia, Espino-Saldaña, Ángeles E., Martínez-Torres, Ataúlfo, Qu, Zhiqiang, Hartzell, H. Criss, Corral-Fernandez, Nancy E., Pérez-Cornejo, Patricia, Arreola, Jorge
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807209/
https://ncbi.nlm.nih.gov/pubmed/29277655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2017.12.009
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