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Voltage- and calcium-dependent gating of TMEM16A/Ano1 chloride channels are physically coupled by the first intracellular loop

Ca(2+)-activated Cl(−) channels (CaCCs) are exceptionally well adapted to subserve diverse physiological roles, from epithelial fluid transport to sensory transduction, because their gating is cooperatively controlled by the interplay between ionotropic and metabotropic signals. A molecular understa...

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Bibliografiske detaljer
Main Authors: Xiao, Qinghuan, Yu, Kuai, Perez-Cornejo, Patricia, Cui, Yuanyuan, Arreola, Jorge, Hartzell, H. Criss
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102354/
https://ncbi.nlm.nih.gov/pubmed/21555582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102147108
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