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Activation of the Ano1 (TMEM16A) chloride channel by calcium is not mediated by calmodulin
The Ca(2+)-activated Cl channel anoctamin-1 (Ano1; Tmem16A) plays a variety of physiological roles, including epithelial fluid secretion. Ano1 is activated by increases in intracellular Ca(2+), but there is uncertainty whether Ca(2+) binds directly to Ano1 or whether phosphorylation or additional Ca...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4001774/ https://ncbi.nlm.nih.gov/pubmed/24420770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201311047 |
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