Extracellular protons enable activation of the calcium‐dependent chloride channel TMEM16A

KEY POINTS: The calcium‐activated chloride channel TMEM16A provides a pathway for chloride ion movements that are key in preventing polyspermy, allowing fluid secretion, controlling blood pressure, and enabling gastrointestinal activity. TMEM16A is opened by voltage‐dependent calcium binding and reg...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Physiol
Egile Nagusiak: Cruz‐Rangel, Silvia, De Jesús‐Pérez, José J., Aréchiga‐Figueroa, Iván A., Rodríguez‐Menchaca, Aldo A., Pérez‐Cornejo, Patricia, Hartzell, H. Criss, Arreola, Jorge
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2017
Gaiak:
Molecular and cellular
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330900/
https://ncbi.nlm.nih.gov/pubmed/27859335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273111
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