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An autoregulatory cell cycle timer integrates growth and specification in chick wing digit development
A fundamental question is how proliferation and growth are timed during embryogenesis. Although it has been suggested that the cell cycle could be a timer, the underlying mechanisms remain elusive. Here we describe a cell cycle timer that operates in Sonic hedgehog (Shh)-expressing polarising region...
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| Опубликовано в: : | eLife |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
eLife Sciences Publications, Ltd
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6777937/ https://ncbi.nlm.nih.gov/pubmed/31545166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47625 |
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