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Inhibition of Shh signalling in the chick wing gives insights into digit patterning and evolution

In an influential model of pattern formation, a gradient of Sonic hedgehog (Shh) signalling in the chick wing bud specifies cells with three antero-posterior positional values, which give rise to three morphologically different digits by a self-organizing mechanism with Turing-like properties. Howev...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Pickering, Joseph, Towers, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087615/
https://ncbi.nlm.nih.gov/pubmed/27702785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.137398
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