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Disrupted hippocampal growth hormone secretagogue receptor 1α interaction with dopamine receptor D1 plays a role in Alzheimer’s disease

Hippocampal lesions are a defining pathology of Alzheimer’s disease (AD). However, the molecular mechanisms that underlie hippocampal synaptic injury in AD have not been fully elucidated. Current therapeutic efforts for AD treatment are not effective in correcting hippocampal synaptic deficits. Grow...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Transl Med
Päätekijät: Tian, Jing, Guo, Lan, Sui, Shaomei, Driskill, Christopher, Phensy, Aarron, Wang, Qi, Gauba, Esha, Zigman, Jeffrey M., Swerdlow, Russell H., Kroener, Sven, Du, Heng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776822/
https://ncbi.nlm.nih.gov/pubmed/31413143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aav6278
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