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Disrupted hippocampal growth hormone secretagogue receptor 1α interaction with dopamine receptor D1 plays a role in Alzheimer’s disease

Hippocampal lesions are a defining pathology of Alzheimer’s disease (AD). However, the molecular mechanisms that underlie hippocampal synaptic injury in AD have not been fully elucidated. Current therapeutic efforts for AD treatment are not effective in correcting hippocampal synaptic deficits. Grow...

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Detalles Bibliográficos
Publicado en:Sci Transl Med
Main Authors: Tian, Jing, Guo, Lan, Sui, Shaomei, Driskill, Christopher, Phensy, Aarron, Wang, Qi, Gauba, Esha, Zigman, Jeffrey M., Swerdlow, Russell H., Kroener, Sven, Du, Heng
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776822/
https://ncbi.nlm.nih.gov/pubmed/31413143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aav6278
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