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Disrupted hippocampal growth hormone secretagogue receptor 1α interaction with dopamine receptor D1 plays a role in Alzheimer’s disease

Hippocampal lesions are a defining pathology of Alzheimer’s disease (AD). However, the molecular mechanisms that underlie hippocampal synaptic injury in AD have not been fully elucidated. Current therapeutic efforts for AD treatment are not effective in correcting hippocampal synaptic deficits. Grow...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Tian, Jing, Guo, Lan, Sui, Shaomei, Driskill, Christopher, Phensy, Aarron, Wang, Qi, Gauba, Esha, Zigman, Jeffrey M., Swerdlow, Russell H., Kroener, Sven, Du, Heng
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776822/
https://ncbi.nlm.nih.gov/pubmed/31413143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aav6278
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