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Lobaplatin promotes (125)I-induced apoptosis and inhibition of proliferation in hepatocellular carcinoma by upregulating PERK-eIF2α-ATF4-CHOP pathway

We investigated the mechanism underlying the effect of a combination treatment of (125)I radioactive seed implantation and lobaplatin (LBP) in hepatocellular carcinoma. The effects of administration of HCC cells and subcutaneous tumor model of mice with different doses of (125)I or a sensitizing con...

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Dades bibliogràfiques
Publicat a:Cell Death Dis
Autors principals: Li, Dong, Wang, Wu-jie, Wang, Yong-zheng, Wang, Yi-biao, Li, Yu-liang
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776519/
https://ncbi.nlm.nih.gov/pubmed/31582720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1918-1
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