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Lobaplatin promotes (125)I-induced apoptosis and inhibition of proliferation in hepatocellular carcinoma by upregulating PERK-eIF2α-ATF4-CHOP pathway

We investigated the mechanism underlying the effect of a combination treatment of (125)I radioactive seed implantation and lobaplatin (LBP) in hepatocellular carcinoma. The effects of administration of HCC cells and subcutaneous tumor model of mice with different doses of (125)I or a sensitizing con...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Li, Dong, Wang, Wu-jie, Wang, Yong-zheng, Wang, Yi-biao, Li, Yu-liang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776519/
https://ncbi.nlm.nih.gov/pubmed/31582720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1918-1
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