Endoplasmic reticulum stress triggers delanzomib-induced apoptosis in HCC cells through the PERK/eIF2α/ATF4/CHOP pathway

For limited clinical benefits and acquired resistance by sorafenib, new therapeutic strategies and molecular targets for the treatment of advanced hepatocellular carcinoma (HCC) are urgently needed. This study aimed to evaluate the potential antitumor effects of the second-generation proteasome inhi...

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Dades bibliogràfiques
Publicat a:Am J Transl Res
Autors principals: Li, Jun, Zhuo, Jian-Yong, Zhou, Wei, Hong, Jia-Wei, Chen, Rong-Gao, Xie, Hai-Yang, Zhou, Lin, Zheng, Shu-Sen, Jiang, Dong-Hai
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2020
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7344101/
https://ncbi.nlm.nih.gov/pubmed/32655816
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