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Endoplasmic reticulum stress triggers delanzomib-induced apoptosis in HCC cells through the PERK/eIF2α/ATF4/CHOP pathway

For limited clinical benefits and acquired resistance by sorafenib, new therapeutic strategies and molecular targets for the treatment of advanced hepatocellular carcinoma (HCC) are urgently needed. This study aimed to evaluate the potential antitumor effects of the second-generation proteasome inhi...

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Bibliografske podrobnosti
izdano v:Am J Transl Res
Main Authors: Li, Jun, Zhuo, Jian-Yong, Zhou, Wei, Hong, Jia-Wei, Chen, Rong-Gao, Xie, Hai-Yang, Zhou, Lin, Zheng, Shu-Sen, Jiang, Dong-Hai
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7344101/
https://ncbi.nlm.nih.gov/pubmed/32655816
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