Endoplasmic reticulum stress triggers delanzomib-induced apoptosis in HCC cells through the PERK/eIF2α/ATF4/CHOP pathway

For limited clinical benefits and acquired resistance by sorafenib, new therapeutic strategies and molecular targets for the treatment of advanced hepatocellular carcinoma (HCC) are urgently needed. This study aimed to evaluate the potential antitumor effects of the second-generation proteasome inhi...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Li, Jun, Zhuo, Jian-Yong, Zhou, Wei, Hong, Jia-Wei, Chen, Rong-Gao, Xie, Hai-Yang, Zhou, Lin, Zheng, Shu-Sen, Jiang, Dong-Hai
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7344101/
https://ncbi.nlm.nih.gov/pubmed/32655816
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