Endoplasmic reticulum stress triggers delanzomib-induced apoptosis in HCC cells through the PERK/eIF2α/ATF4/CHOP pathway

For limited clinical benefits and acquired resistance by sorafenib, new therapeutic strategies and molecular targets for the treatment of advanced hepatocellular carcinoma (HCC) are urgently needed. This study aimed to evaluate the potential antitumor effects of the second-generation proteasome inhi...

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Pubblicato in:Am J Transl Res
Autori principali: Li, Jun, Zhuo, Jian-Yong, Zhou, Wei, Hong, Jia-Wei, Chen, Rong-Gao, Xie, Hai-Yang, Zhou, Lin, Zheng, Shu-Sen, Jiang, Dong-Hai
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2020
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7344101/
https://ncbi.nlm.nih.gov/pubmed/32655816
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