PERK‐eIF2α‐ATF4‐CHOP Signaling Contributes to TNFα‐Induced Vascular Calcification

BACKGROUND: Vascular calcification is a common feature in patients with chronic kidney disease (CKD). CKD increases serum levels of tumor necrosis factor‐α (TNFα), a critical mediator of vascular calcification. However, the molecular mechanism by which TNFα promotes CKD‐dependent vascular calcificat...

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Hlavní autoři: Masuda, Masashi, Miyazaki‐Anzai, Shinobu, Levi, Moshe, Ting, Tabitha C., Miyazaki, Makoto
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2013
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835225/
https://ncbi.nlm.nih.gov/pubmed/24008080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.113.000238
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