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Lobaplatin promotes (125)I-induced apoptosis and inhibition of proliferation in hepatocellular carcinoma by upregulating PERK-eIF2α-ATF4-CHOP pathway

We investigated the mechanism underlying the effect of a combination treatment of (125)I radioactive seed implantation and lobaplatin (LBP) in hepatocellular carcinoma. The effects of administration of HCC cells and subcutaneous tumor model of mice with different doses of (125)I or a sensitizing con...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Li, Dong, Wang, Wu-jie, Wang, Yong-zheng, Wang, Yi-biao, Li, Yu-liang
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776519/
https://ncbi.nlm.nih.gov/pubmed/31582720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1918-1
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