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Lobaplatin promotes (125)I-induced apoptosis and inhibition of proliferation in hepatocellular carcinoma by upregulating PERK-eIF2α-ATF4-CHOP pathway

We investigated the mechanism underlying the effect of a combination treatment of (125)I radioactive seed implantation and lobaplatin (LBP) in hepatocellular carcinoma. The effects of administration of HCC cells and subcutaneous tumor model of mice with different doses of (125)I or a sensitizing con...

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Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Li, Dong, Wang, Wu-jie, Wang, Yong-zheng, Wang, Yi-biao, Li, Yu-liang
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776519/
https://ncbi.nlm.nih.gov/pubmed/31582720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1918-1
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