Wordt geladen...

6,7-Dihydroxyisoindolin-1-one and 7,8-Dihydroxy-3,4-Dihydroisoquinolin-1(2H)-one Based HIV-1 Integrase Inhibitors

Integrase (IN) is an essential viral enzyme required for HIV-1 replication, which has been targeted by anti-AIDS therapeutics. Integrase strand transfer inhibitors (INSTIs) represent a new class of antiretroviral agents developed for the treatment of HIV-1 infections. Important structural features t...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Curr Top Med Chem
Hoofdauteurs: Zhao, Xue Zhi, Métifiot, Mathieu, Smith, Steven J., Maddali, Kasthuraiah, Marchand, Christophe, Hughes, Stephen H., Pommier, Yves, Burke, Terrence R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775782/
https://ncbi.nlm.nih.gov/pubmed/26268341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1568026615666150813150058
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!