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Gram-negative synergy and mechanism of action of alkynyl bisbenzimidazoles
Bisbenzimidazoles with terminal alkynyl linkers, selective inhibitors of bacterial topoisomerase I, have been evaluated using bacterial cytological profiling (BCP) to ascertain their mechanism of action and screened for synergism to improve Gram-negative bacterial coverage. Principal component analy...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6775084/ https://ncbi.nlm.nih.gov/pubmed/31578425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48898-4 |
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