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Potent inhibition of miR-27a by neomycin–bisbenzimidazole conjugates
miRNAs are important components of regulatory networks that control gene expression and have implications in various diseases including cancer. Targeting oncogenic miRNAs with small molecules is currently being explored to develop cancer therapeutics. Here, we report the development of dual binding...
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| Publié dans: | Chem Sci |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Royal Society of Chemistry
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5947510/ https://ncbi.nlm.nih.gov/pubmed/29861909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc01969a |
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