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Potent inhibition of miR-27a by neomycin–bisbenzimidazole conjugates

miRNAs are important components of regulatory networks that control gene expression and have implications in various diseases including cancer. Targeting oncogenic miRNAs with small molecules is currently being explored to develop cancer therapeutics. Here, we report the development of dual binding...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Chem Sci
Main Authors: Nahar, Smita, Ranjan, Nihar, Ray, Arjun, Arya, Dev P., Maiti, Souvik
Format: Artigo
Jezik:Inglês
Izdano: Royal Society of Chemistry 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5947510/
https://ncbi.nlm.nih.gov/pubmed/29861909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc01969a
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