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Potent inhibition of miR-27a by neomycin–bisbenzimidazole conjugates

miRNAs are important components of regulatory networks that control gene expression and have implications in various diseases including cancer. Targeting oncogenic miRNAs with small molecules is currently being explored to develop cancer therapeutics. Here, we report the development of dual binding...

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Vydáno v:Chem Sci
Hlavní autoři: Nahar, Smita, Ranjan, Nihar, Ray, Arjun, Arya, Dev P., Maiti, Souvik
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5947510/
https://ncbi.nlm.nih.gov/pubmed/29861909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc01969a
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