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Gram-negative synergy and mechanism of action of alkynyl bisbenzimidazoles

Bisbenzimidazoles with terminal alkynyl linkers, selective inhibitors of bacterial topoisomerase I, have been evaluated using bacterial cytological profiling (BCP) to ascertain their mechanism of action and screened for synergism to improve Gram-negative bacterial coverage. Principal component analy...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Chamberlin, Jordan, Story, Sandra, Ranjan, Nihar, Chesser, Geoffrey, Arya, Dev P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775084/
https://ncbi.nlm.nih.gov/pubmed/31578425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48898-4
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