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Gram-negative synergy and mechanism of action of alkynyl bisbenzimidazoles

Bisbenzimidazoles with terminal alkynyl linkers, selective inhibitors of bacterial topoisomerase I, have been evaluated using bacterial cytological profiling (BCP) to ascertain their mechanism of action and screened for synergism to improve Gram-negative bacterial coverage. Principal component analy...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Chamberlin, Jordan, Story, Sandra, Ranjan, Nihar, Chesser, Geoffrey, Arya, Dev P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775084/
https://ncbi.nlm.nih.gov/pubmed/31578425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48898-4
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