Activation of JAK/STAT signaling in megakaryocytes sustains myeloproliferation in vivo

PURPOSE: The myeloproliferative neoplasms (MPNs), including Polycythemia Vera (PV), Essential Thrombocythemia (ET), and Primary Myelofibrosis (PMF), are characterized by the expansion of the erythroid, megakaryocytic, and granulocytic lineages. A common feature of these disorders is the presence of...

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Détails bibliographiques
Publié dans:Clin Cancer Res
Auteurs principaux: Woods, Brittany, Chen, Wei, Chiu, Sophia, Marinaccio, Christian, Fu, Chunling, Gu, Lilly, Bulic, Marinka, Yang, Qiong, Zouak, Anouar, Jia, Shengxian, Suraneni, Praveen Kumar, Xu, Kailin, Levine, Ross L., Crispino, John D., Wen, Qiang Jeremy
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774846/
https://ncbi.nlm.nih.gov/pubmed/31217200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-4089
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