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JAK2(V617F)-mutant megakaryocytes contribute to hematopoietic stem/progenitor cell expansion in a model of murine myeloproliferation

The myeloproliferative neoplasms (MPNs) are characterized by hematopoietic stem/progenitor cell (HSPC) expansion and overproduction of mature blood cells. The JAK2(V617F) mutation is present in hematopoietic cells in a majority of patients with MPNs, but the mechanism(s) responsible for MPN stem cel...

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Detaylı Bibliyografya
Yayımlandı:Leukemia
Asıl Yazarlar: Zhan, H, Ma, Y, Lin, CHS, Kaushansky, K
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5158308/
https://ncbi.nlm.nih.gov/pubmed/27133820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.114
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