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The JAK2V617F-bearing vascular niche promotes clonal expansion in myeloproliferative neoplasms
The acquired kinase mutation JAK2V617F plays a central role in myeloproliferative neoplasms (MPNs). However, the mechanisms responsible for the malignant hematopoietic stem/progenitor cell (HSPC) expansion seen in patients with MPNs are not fully understood, limiting the effectiveness of current tre...
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| Publicado no: | Leukemia |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5783797/ https://ncbi.nlm.nih.gov/pubmed/28744010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2017.233 |
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