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JAK2(V617F)-mutant Vascular Niche Contributes to JAK2(V617F) Clonal Expansion in Myeloproliferative Neoplasms
The myeloproliferative neoplasms (MPNs) are characterized by hematopoietic stem/progenitor cell (HSPC) expansion and overproduction of blood cells. The acquired mutation JAK2(V617F) plays a central role in these disorders. Mechanisms responsible for MPN HSPC expansion is not fully understood, limiti...
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| Veröffentlicht in: | Blood Cells Mol Dis |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5135612/ https://ncbi.nlm.nih.gov/pubmed/27865175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2016.09.004 |
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