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JAK2V617F-bearing vascular niche enhances malignant hematopoietic regeneration following radiation injury

Myeloproliferative neoplasms are clonal stem cell disorders characterized by hematopoietic stem/progenitor cell expansion. The acquired kinase mutation JAK2V617F plays a central role in these disorders. Abnormalities of the marrow microenvironment are beginning to be recognized as an important facto...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Lin, Chi Hua Sarah, Zhang, Yu, Kaushansky, Kenneth, Zhan, Huichun
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6029534/
https://ncbi.nlm.nih.gov/pubmed/29567773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2017.185736
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