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Developments in the space of new MAPK pathway inhibitors for BRAF-mutant melanoma

The characterization of the MAPK signaling pathway has led to the development of multiple promising targeted therapy options for a subset of patients with metastatic melanoma. The combination of BRAF and MEK inhibitors represents an FDA-approved standard of care in patients with metastatic and resec...

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Bibliographic Details
Published in:Clin Cancer Res
Main Authors: Cohen, Justine V., Sullivan, Ryan J.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774830/
https://ncbi.nlm.nih.gov/pubmed/30992297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-0836
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