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Potentiated Opioid Analgesia in Norepinephrine Transporter Knock-Out Mice

Several studies have shown that activation of α(2)-adrenergic receptors (α(2)ARs) leads to mild analgesic effects. Tricyclic antidepressants (TCAs), such as desipramine (DMI), which block norepinephrine transporters (NETs), also produce mild antinociception. The coadministration of either α(2)AR ago...

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Bibliografski detalji
Izdano u:J Neurosci
Glavni autori: Bohn, Laura M., Xu, Fei, Gainetdinov, Raul R., Caron, Marc G.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2000
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773039/
https://ncbi.nlm.nih.gov/pubmed/11124980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-24-09040.2000
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