Enhanced Rewarding Properties of Morphine, but not Cocaine, in βarrestin-2 Knock-Out Mice

The reinforcing and psychomotor effects of morphine involve opiate stimulation of the dopaminergic system via activation of μ-opioid receptors (μOR). Both μ-opioid and dopamine receptors are members of the G-protein-coupled receptor (GPCR) family of proteins. GPCRs are known to undergo desensitizati...

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Foilsithe in:J Neurosci
Main Authors: Bohn, Laura M., Gainetdinov, Raul R., Sotnikova, Tatyana D., Medvedev, Ivan O., Lefkowitz, Robert J., Dykstra, Linda A., Caron, Marc G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 2003
Ábhair:
Behavioral/Systems/Cognitive
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741024/
https://ncbi.nlm.nih.gov/pubmed/14614085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-32-10265.2003
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