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Neurons Regulate Extracellular Levels of Amyloid β-Protein via Proteolysis by Insulin-Degrading Enzyme
Progressive cerebral accumulation of amyloid β-protein (Aβ) is an early and invariant feature of Alzheimer's disease. Little is known about how Aβ, after being secreted, is degraded and cleared from the extracellular space of the brain. Defective Aβ degradation could be a risk factor for the de...
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| Vydáno v: | J Neurosci |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Society for Neuroscience
2000
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6772918/ https://ncbi.nlm.nih.gov/pubmed/10684867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-05-01657.2000 |
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