Evidence for Seeding of β-Amyloid by Intracerebral Infusion of Alzheimer Brain Extracts in β-Amyloid Precursor Protein-Transgenic Mice

Many neurodegenerative diseases are associated with the abnormal sequestration of disease-specific proteins in the brain, but the events that initiate this process remain unclear. To determine whether the deposition of the β-amyloid peptide (Aβ), a key pathological feature of Alzheimer's diseas...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Kane, Michael D., Lipinski, William J., Callahan, Michael J., Bian, Feng, Durham, Robert A., Schwarz, Roy D., Roher, Alex E., Walker, Lary C.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2000
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772682/
https://ncbi.nlm.nih.gov/pubmed/10804202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-10-03606.2000
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