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Soluble Aβ Seeds Are Potent Inducers of Cerebral β-Amyloid Deposition

Cerebral β-amyloidosis and associated pathologies can be exogenously induced by the intracerebral injection of small amounts of pathogenic Aβ-containing brain extract into young β-amyloid precursor protein (APP) transgenic mice. The probable β-amyloid-inducing factor in the brain extract has been id...

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Autori principali: Langer, Franziska, Eisele, Yvonne S., Fritschi, Sarah K., Staufenbiel, Matthias, Walker, Lary C., Jucker, Mathias
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229270/
https://ncbi.nlm.nih.gov/pubmed/21994365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3088-11.2011
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