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Progression of Seed‐Induced Aβ Deposition within the Limbic Connectome

An important early event in the pathogenesis of Alzheimer's disease (AD) is the aberrant polymerization and extracellular accumulation of amyloid‐β peptide (Aβ). In young transgenic mice expressing the human Aβ‐precursor protein (APP), deposits of Aβ can be induced by the inoculation of minute...

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Detalles Bibliográficos
Publicado en:Brain Pathol
Main Authors: Ye, Lan, Hamaguchi, Tsuyoshi, Fritschi, Sarah K., Eisele, Yvonne S., Obermüller, Ulrike, Jucker, Mathias, Walker, Lary C.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530099/
https://ncbi.nlm.nih.gov/pubmed/25677332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12252
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