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Progression of Seed‐Induced Aβ Deposition within the Limbic Connectome

An important early event in the pathogenesis of Alzheimer's disease (AD) is the aberrant polymerization and extracellular accumulation of amyloid‐β peptide (Aβ). In young transgenic mice expressing the human Aβ‐precursor protein (APP), deposits of Aβ can be induced by the inoculation of minute...

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Bibliografiske detaljer
Udgivet i:Brain Pathol
Main Authors: Ye, Lan, Hamaguchi, Tsuyoshi, Fritschi, Sarah K., Eisele, Yvonne S., Obermüller, Ulrike, Jucker, Mathias, Walker, Lary C.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530099/
https://ncbi.nlm.nih.gov/pubmed/25677332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12252
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