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Multiple Factors Contribute to the Peripheral Induction of Cerebral β-Amyloidosis

Deposition of aggregated amyloid-β (Aβ) peptide in brain is an early event and hallmark pathology of Alzheimer's disease and cerebral Aβ angiopathy. Experimental evidence supports the concept that Aβ multimers can act as seeds and structurally corrupt other Aβ peptides by a self-propagating mec...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Eisele, Yvonne S., Fritschi, Sarah K., Hamaguchi, Tsuyoshi, Obermüller, Ulrike, Füger, Petra, Skodras, Angelos, Schäfer, Claudia, Odenthal, Jörg, Heikenwalder, Mathias, Staufenbiel, Matthias, Jucker, Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608275/
https://ncbi.nlm.nih.gov/pubmed/25080588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1608-14.2014
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