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Multiple Factors Contribute to the Peripheral Induction of Cerebral β-Amyloidosis

Deposition of aggregated amyloid-β (Aβ) peptide in brain is an early event and hallmark pathology of Alzheimer's disease and cerebral Aβ angiopathy. Experimental evidence supports the concept that Aβ multimers can act as seeds and structurally corrupt other Aβ peptides by a self-propagating mec...

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Publicat a:J Neurosci
Autors principals: Eisele, Yvonne S., Fritschi, Sarah K., Hamaguchi, Tsuyoshi, Obermüller, Ulrike, Füger, Petra, Skodras, Angelos, Schäfer, Claudia, Odenthal, Jörg, Heikenwalder, Mathias, Staufenbiel, Matthias, Jucker, Mathias
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608275/
https://ncbi.nlm.nih.gov/pubmed/25080588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1608-14.2014
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