Induction of cerebral β-amyloidosis: Intracerebral versus systemic Aβ inoculation

Despite the importance of the aberrant polymerization of Aβ in the early pathogenic cascade of Alzheimer's disease, little is known about the induction of Aβ aggregation in vivo. Here we show that induction of cerebral β-amyloidosis can be achieved in many different brain areas of APP23 transge...

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Detalhes bibliográficos
Main Authors: Eisele, Yvonne S., Bolmont, Tristan, Heikenwalder, Mathias, Langer, Franziska, Jacobson, Laura H., Yan, Zheng-Xin, Roth, Klaus, Aguzzi, Adriano, Staufenbiel, Matthias, Walker, Lary C., Jucker, Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722323/
https://ncbi.nlm.nih.gov/pubmed/19622727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903200106
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