Highly potent soluble amyloid-β seeds in human Alzheimer brain but not cerebrospinal fluid

The soluble fraction of brain samples from patients with Alzheimer’s disease contains highly biologically active amyloid-β seeds. In this study, we sought to assess the potency of soluble amyloid-β seeds derived from the brain and cerebrospinal fluid. Soluble Alzheimer’s disease brain extracts were...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Fritschi, Sarah K., Langer, Franziska, Kaeser, Stephan A., Maia, Luis F., Portelius, Erik, Pinotsi, Dorothea, Kaminski, Clemens F., Winkler, David T., Maetzler, Walter, Keyvani, Kathy, Spitzer, Philipp, Wiltfang, Jens, Kaminski Schierle, Gabriele S., Zetterberg, Henrik, Staufenbiel, Matthias, Jucker, Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367518/
https://ncbi.nlm.nih.gov/pubmed/25212850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awu255
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