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Highly potent soluble amyloid-β seeds in human Alzheimer brain but not cerebrospinal fluid

The soluble fraction of brain samples from patients with Alzheimer’s disease contains highly biologically active amyloid-β seeds. In this study, we sought to assess the potency of soluble amyloid-β seeds derived from the brain and cerebrospinal fluid. Soluble Alzheimer’s disease brain extracts were...

詳細記述

保存先:
書誌詳細
出版年:Brain
主要な著者: Fritschi, Sarah K., Langer, Franziska, Kaeser, Stephan A., Maia, Luis F., Portelius, Erik, Pinotsi, Dorothea, Kaminski, Clemens F., Winkler, David T., Maetzler, Walter, Keyvani, Kathy, Spitzer, Philipp, Wiltfang, Jens, Kaminski Schierle, Gabriele S., Zetterberg, Henrik, Staufenbiel, Matthias, Jucker, Mathias
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367518/
https://ncbi.nlm.nih.gov/pubmed/25212850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awu255
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