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Highly potent soluble amyloid-β seeds in human Alzheimer brain but not cerebrospinal fluid

The soluble fraction of brain samples from patients with Alzheimer’s disease contains highly biologically active amyloid-β seeds. In this study, we sought to assess the potency of soluble amyloid-β seeds derived from the brain and cerebrospinal fluid. Soluble Alzheimer’s disease brain extracts were...

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Dades bibliogràfiques
Publicat a:Brain
Autors principals: Fritschi, Sarah K., Langer, Franziska, Kaeser, Stephan A., Maia, Luis F., Portelius, Erik, Pinotsi, Dorothea, Kaminski, Clemens F., Winkler, David T., Maetzler, Walter, Keyvani, Kathy, Spitzer, Philipp, Wiltfang, Jens, Kaminski Schierle, Gabriele S., Zetterberg, Henrik, Staufenbiel, Matthias, Jucker, Mathias
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367518/
https://ncbi.nlm.nih.gov/pubmed/25212850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awu255
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