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Exacerbated Responses to Oxidative Stress by an Na(+)Load in Isolated Nerve Terminals: the Role of ATP Depletion and Rise of [Ca(2+)](i)

We have explored the consequences of a [Na(+)](i) load and oxidative stress in isolated nerve terminals. The Na(+) load was achieved by veratridine (5–40 μm), which allows Na(+) entry via a voltage-operated Na(+) channel, and oxidative stress was induced by hydrogen peroxide (0.1–0.5 mm). Remarkably...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Chinopoulos, Christos, Tretter, Laszlo, Rozsa, Adrienn, Adam-Vizi, Vera
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772497/
https://ncbi.nlm.nih.gov/pubmed/10704483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-06-02094.2000
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